The Studies Behind Aseptrol®
These studies were published externally and were not conducted by Oxidium Technologies. Refer to the master label for guidance on all efficacy claims and contact times.
A collection of published studies on Aseptrol® chlorine dioxide chemistries.
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Gnotobiotic Isolator Sterilization: Chlorine Dioxide vs. Peroxides
Journal of the American Association for Laboratory Animal Science 58(5):558–568.
UC San Diego. PMID: 31319899
Researchers at UC San Diego evaluated multiple disinfectant classes, including chlorine dioxide, peroxide-based products, and standard bleach, for sterilizing flexible vinyl gnotobiotic rodent isolators, one of the most demanding disinfection environments in laboratory animal science. The study compared not just kill efficacy but real-world practicality across an entire class of sterilization methods used in germ-free research. Chlorine dioxide chemistry performed as a strong, reliable option in this head-to-head evaluation, giving gnotobiotic facilities using Aseptrol-based products independent, published support for the chemistry behind their sterilization protocol.
Choosing the Right Disinfectant: Efficacy, Safety, and Animal Behavior
Journal of the American Association for Laboratory Animal Science 55(2):175–188.
UCLA. PMID: 27025810
This UCLA study set out to answer a question every vivarium manager faces: which disinfectant is actually the best overall choice, not just the most potent? The research team built a viral-vector efficacy assay, reviewed safety data sheets across disinfectant classes, and, notably, ran behavioral testing on three mouse strains (Swiss Webster, C57Bl/6, BALB/c) to see which chemistries animals would actively avoid. Their finding: the "gold standard" hypochlorite (bleach) and peroxide-based products were both clearly aversive to mice, while MB-10 (the same chlorine dioxide chemistry behind Aseptrol® S10-Tab) was included in the same behavioral testing. This is one of the few published studies to treat animal welfare as a core disinfectant-selection criterion, exactly the kind of independent, multi-factor comparison that supports chlorine dioxide's positioning as a lower-aversion alternative in animal research settings.
Sporicidal Activity Against Bacillus anthracis (Anthrax)
Study performed with support from NIAID contract N01-AI-30065; no funding from the manufacturer of Aseptrol® S10-Tab (sold as Vimoba™ by Quip Laboratories).
In an NIH-funded, manufacturer-independent study, researchers directly tested Aseptrol® S10-Tab (sold as Vimoba™ by Quip Laboratories) against Bacillus anthracis Sterne strain spores, one of the most difficult organisms to kill with any disinfectant. Aseptrol® S10-Tab demonstrated potent biocidal activity against anthrax spores at multiple concentrations, and the study went further to establish practical field guidance: how long prepared solution retains full potency in spray bottles, and how supplementing with small amounts of bleach can extend usable shelf life. Because this research was independently funded (not by the manufacturer) and targeted one of the most resistant pathogens available for testing, it is a notable independent data point on chlorine dioxide's sporicidal potential.
Chlorine Dioxide Tablets vs. Cryptosporidium Oocysts
Environmental Science & Technology 48(10):5849–5856. CDC (Waterborne Disease Prevention Branch). PMID: 24797292
Conducted by CDC researchers, this study used Aseptrol S-Tab10 tablets as the chlorine dioxide source to test inactivation of Cryptosporidium oocysts, a notoriously chlorine-resistant parasite responsible for recreational water illness outbreaks. The study established specific contact times and concentrations needed to achieve 3-log (99.9%) inactivation, giving Aseptrol-based chemistry a place in the peer-reviewed literature as a validated tool against one of the toughest pathogens regulators and public health officials track. A federal agency (CDC) chose this specific tablet formulation to test and published the resulting protocol, a meaningful, independent data point on Cryptosporidium inactivation.
Chlorine Dioxide (Aseptrol) vs. Hepatitis B Virus
Pathogens 10(8):1017. Primary source cited therein: Ebonwu et al. (2010).
A 2021 peer-reviewed synthesis of chlorine dioxide's antiviral literature specifically cites Aseptrol® by name, reporting that its noncorrosive chlorine dioxide formula eliminated the Hepatitis B virus genome at 24 mg/L after a 5-minute contact time, a 99.99% reduction. Being named specifically (rather than just "chlorine dioxide products" generally) in a broader academic review of bloodborne virus disinfection is a strong, independent nod to the product's real-world virucidal performance against one of the most consequential bloodborne pathogens in healthcare settings.
Aseptrol vs. Presept: Disinfecting Dental Impression Materials
Patel M, Ebonwu J, Cutler E. SADJ 2012;67(7):364, 366–369.
This study directly compared Aseptrol against a chlorite-based competitor (Presept) for disinfecting irreversible hydrocolloid (alginate) dental impressions, material contaminated with a panel of organisms including C. albicans, S. aureus, P. aeruginosa, S. mutans, and B. subtilis spores. Aseptrol achieved a consistent 99.99% reduction in vegetative organisms after just 30 seconds of immersion, and fully inactivated spores in 1.5 minutes, a meaningfully shorter contact time than its comparator needed for spores (5 minutes). Because alginate is dimensionally unstable and can degrade with extended soak times, this shorter effective contact time is a genuine practical advantage: faster disinfection means less risk of distorting the impression material itself.
Irreversible Hydrocolloid Impression Disinfection with Chlorinated Compounds
This study evaluated a chlorine dioxide-based disinfectant (Aseptrol) against irreversible hydrocolloid impression material, supporting the product's antimicrobial efficacy and suitability for clinical short-contact-time use.